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Eyelid Lesion Biopsy

An eyelid lesion biopsy is a procedure used to remove a small sample of tissue from a lesion (growth or abnormal area) on the eyelid. Actinic keratosis, a common precancerous condition presenting as round, scaly, hyper-keratotic plaques, often resembling sandpaper, may also require biopsy. This biopsy helps determine whether the lesion is benign (non-cancerous) or malignant (cancerous).

Also known as: Eyelid Growth Biopsy, Eyelid Tumour Biopsy

What is an Eyelid Lesion Biopsy?

An eyelid lesion biopsy is a medical procedure designed to remove a small sample of tissue from a suspicious growth or lesion on the eyelid. This sample is then meticulously examined under a microscope by a pathologist to determine the nature of the lesion—whether it is benign or malignant—and to identify the specific type of cells present. This crucial information helps in formulating the best treatment plan for the patient.

Typically performed in a doctor’s office or clinic, the biopsy procedure is relatively quick, usually taking about 15-20 minutes. The area around the lesion is numbed with local anaesthesia to ensure comfort, and a small tissue sample is removed using a specialised instrument. This sample is then sent to a laboratory for detailed examination.

There are several types of biopsies that can be performed on eyelid lesions, including:

  • Excisional Biopsy: Removal of the entire lesion.
  • Incisional Biopsy: Removal of a portion of the lesion.
  • Punch Biopsy: Using a circular blade to remove a small core of tissue.
  • Shave Biopsy: Shaving off the top layers of the lesion.

The choice of biopsy type depends on the lesion’s size, location, and the suspected diagnosis, ensuring the most accurate and informative results.

Everything You Need to Know

Lesions on the eyelid can take various forms, such as cysts, moles, or tumours, and while many are harmless, some may require further investigation to rule out conditions such as skin cancer. The biopsy is performed with precision, minimising damage to the delicate eyelid area, and provides essential information to guide appropriate treatment.

An eyelid lesion biopsy is a straightforward and highly informative procedure, helping patients and doctors understand the nature of the lesion. Here are the key benefits of the procedure:

  • Accurate Diagnosis: The biopsy provides a definitive diagnosis, distinguishing between benign and malignant lesions.
  • Guides Treatment: Knowing the nature of the lesion allows doctors to develop an appropriate treatment plan, whether it requires further surgery or monitoring.
  • Minimally Invasive: The biopsy is a minor procedure with minimal discomfort and a quick recovery time.

When is an Eyelid Lesion Biopsy Needed for Benign Eyelid Lesions?

An eyelid lesion biopsy is typically recommended when there is an abnormal growth or lesion on the eyelid that has changed in size, shape, or colour, or if there is concern that it could be malignant. Lesions that are rapidly growing, irregularly shaped, or causing discomfort, irritation, or vision problems are often biopsied to rule out conditions such as basal cell carcinoma, squamous cell carcinoma, melanoma, basal cell cancer, or sebaceous carcinoma.

In some cases, benign lesions like cysts or moles may also require a biopsy if they are causing cosmetic concerns or discomfort.

Types of Eyelid Lesions

Eyelid lesions can be broadly classified into benign, malignant, and infectious categories, each with distinct characteristics and implications.

Before Surgery

Consultation

During your initial consultation, your doctor will examine the lesion and review your medical history. They will also check for benign eyelid lesions, which are predominantly non-cancerous, and assess their clinical characteristics. They may take a detailed look at the size, location, and appearance of the lesion to assess whether a biopsy is necessary. You will also discuss the biopsy procedure, any risks, and what to expect during recovery.

Pre-Procedure Instructions

Before your biopsy, you may receive specific instructions from your doctor, including:

  • Medication Adjustments: If you take blood thinners, your doctor may advise you to stop them a few days before the procedure to reduce the risk of bleeding.
  • Skin Preparation: Your doctor may provide guidance on cleaning the area around the eyelid to reduce the risk of infection before the biopsy.
  • Healthy Lifestyle: Eating well and avoiding smoking can improve your recovery and reduce complications.

These simple preparations help ensure the biopsy is performed safely and successfully.

During the Biopsy

Anaesthesia

A local anaesthetic will be applied to numb the eyelid, ensuring that you do not feel pain during the biopsy. You will remain awake throughout the procedure, but the area will be completely numbed.

Surgical Process for Eyelid Lesion Biopsy with Mohs Micrographic Surgery

The biopsy procedure involves carefully removing a small portion or the entirety of the lesion, depending on its size and appearance, with particular attention to the eyelid margin as a critical area for examination. It is crucial to avoid necrotic tissue during the biopsy to ensure an accurate diagnosis by sampling healthy tissue adjacent to the lesion. The sample will then be sent to a laboratory for testing to determine whether it is benign or malignant. The procedure typically takes around 20 to 30 minutes and is performed as an outpatient procedure, meaning you can go home the same day.

Your surgeon will make sure the biopsy is done with precision to minimise scarring and maintain the natural contour of the eyelid.

 

After the Biopsy

After the biopsy, it is important to care for the area properly to ensure quick healing and prevent infection.

Immediate Post-Op Care

Following the biopsy, you may experience mild discomfort, swelling, or bruising around the eyelid, but this should subside within a few days. Preventing infectious lesions during post-op care is crucial to avoid complications. Your doctor will provide instructions for keeping the area clean, and you may be given antibiotic ointment to prevent infection.

It’s important to avoid rubbing or touching the area, and you may need to apply a cold compress to reduce swelling. Over-the-counter pain relief can help manage any discomfort.

Long-Term Recovery

Most patients recover from an eyelid lesion biopsy within a week or two. It is important to note that multiple lesions can occur, necessitating ongoing monitoring and potential additional treatments. During this time, it’s essential to avoid strenuous activities or situations that might cause you to touch or strain the area. Your doctor will schedule a follow-up appointment to discuss the biopsy results and any further treatment, if necessary. If the lesion was found to be benign, no further treatment may be required, but if it is malignant, your doctor will explain the next steps, which may include additional surgery or treatment.

Understanding Your Biopsy Results

Once the biopsy is performed, the tissue sample is sent to a laboratory where a pathologist examines it under a microscope. The pathologist’s analysis will reveal whether the lesion is benign or malignant and identify the specific type of cells present.

The biopsy results will provide critical information, including:

  • Benign or Malignant: Determining if the lesion is non-cancerous or cancerous.
  • Type of Cancer: If malignant, identifying the specific type of cancer, such as basal cell carcinoma or squamous cell carcinoma.
  • Severity: Assessing the depth of invasion and whether there is lymph node involvement.

If the biopsy results indicate a benign lesion, no further treatment may be necessary. However, if the lesion is malignant, additional treatment will be required to remove the cancer and prevent its spread. Your doctor will discuss the results with you in detail and outline the next steps in your treatment plan.

 

Appointment and Treatment Plan

01

Initial Consultation

During your first consultation, your doctor will assess the lesion and determine whether a biopsy is necessary to evaluate its nature.

02

The Biopsy Procedure

The biopsy will be performed using local anaesthesia to ensure your comfort. A sample of the lesion will be removed for testing.

03

Results and Next Steps

Once the biopsy results are ready, your doctor will meet with you to discuss the findings and any additional treatment that may be needed.

 

Top Tips

  • Avoid Rubbing the Area: Keep your hands away from the biopsy site to prevent irritation or infection.
  • Use a Cold Compress: If there is swelling, a cold compress can help reduce discomfort.
  • Follow Aftercare Instructions: Your doctor will provide specific aftercare guidelines, including using antibiotic ointment as directed.
  • Attend Follow-Up Appointments: It’s important to return for any scheduled follow-up visits to discuss biopsy results and further treatment options, if necessary.
  • Be Aware of Common Conditions: During recovery, be aware of conditions like epidermal inclusion cysts and sebaceous cysts. These benign lesions can appear as elevated, smooth, and progressively growing, and accurate diagnosis is crucial for appropriate management.

How to pay for your treatment

If you’re… paying for yourself

Did you know you don’t need private medical insurance to come to St John & St Elizabeth Hospital? As a self-pay patient, you can access safe, outstanding quality health care at times to suit you.

For scans and tests, as well as to see most consultants, you’ll still need to be referred by a medical professional like your GP, but as a self-pay patient, the process is more straightforward. You won’t need authorisation from an insurance provider, and you’ll have greater choice of consultant and appointment times.

If you’re… insured

St John & St Elizabeth Hospital is approved by all major medical insurance companies. If you have a personal private health insurance policy, or your company provide it for you, you can use it to pay for your care from your initial consultation through to treatment, surgery and aftercare such as physiotherapy. Not all private health insurance plans cover the same things. It’s very important to check exactly what you are covered for with your insurance provider.